产品货号：
Z36540
中文名称：
Importin Beta/KPNB1抗体
英文名称：
Anti-Importin Beta/KPNB1 Antibody (Clone#3I11F2)
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Importin Beta/KPNB1 Antibody (Clone#3I11F2) |
| 指标别名 | IMB1;Impnb;Importin 90;Importin subunit beta 1;IPO1;IPOB;karyopherin (importin) beta 1;Karyopherin subunit beta 1;KPNB1;NTF97;Nuclear factor p97;PTAC97 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | KPNB1 |
| 克隆号 | 3I11F2 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2b |
| 免疫原 | E.coli-derived human KPNB1 recombinant protein (Position:E8-A876). |
| 实际分子量 | 97KD |
| 成分 | Each vial contains 4mg Trehalose,0.9mg NaCl and 0.2mg Na2HPO4. |
| 纯化方式 | protein G/A purified |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene.Nucleocytoplasmic transport,a signal- and energy-dependent process,takes place through nuclear pore complexes embedded in the nuclear envelope.The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor,a heterodimer of importin alpha and beta subunits also known as karyopherins.Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex.In the presence of nucleoside triphosphates and the small GTP binding protein Ran,the complex moves into the nuclear pore complex and the importin subunits dissociate.Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex.The protein encoded by this gene is a member of the importin beta family.Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q14974 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
| 基因名全称 | karyopherin subunit beta 1 |
| 蛋白名全称 | Importin subunit beta-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow Cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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